Lice infestations are common in toddlers, particularly after exposure in communal settings like school or play areas. Use a pediatrician-approved anti-lice shampoo, applying it carefully to the scalp and hair shafts as directed, and follow up by meticulously using a fine-toothed nit comb to remove all eggs. It is important to treat all family members simultaneously to prevent re-infestation and wash all bedding and soft toys in hot water to eliminate any remaining lice or eggs.